Genetic imbalances revealed by comparative genomic hybridization in osteosarcomas
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چکیده
منابع مشابه
Genomic imbalances in childhood medulloblastoma by comparative genomic hybridization
We used comparative genomic hybridization (CGH) technique to identify the genetic changes in 12 childhood medulloblastoma samples obtained from archived paraffinembedded tissues belonging to children (0.7-15 years-old) using double step degenerate oligonucleotide-primed polymerase chain reaction (DOP-PCR). CGH analysis showed that the most common genetic alterations were gains of chromosomes 4p...
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Renal cell carcinoma (RCC) accounts for approximately 3% of all new cancer cases. Although the classification of RCC is based mainly on histology, this method is not always accurate. We applied comparative genomic hybridization (CGH) to determine genomic alterations in 46 cases of different RCC histological subtypes [10 cases of clear cell RCC (CCRCC), 13 cases of papillary RCC (PRCC), 12 cases...
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Comparative genomic hybridization was used to compare genetic diversity of five strains of Leptospira (Leptospira interrogans serovars Bratislava, Canicola, and Hebdomadis and Leptospira kirschneri serovars Cynopteri and Grippotyphosa). The array was designed based on two available sequenced Leptospira reference genomes, those of L. interrogans serovar Copenhageni and L. interrogans serovar Lai...
متن کاملGenomic imbalances detected by comparative genomic hybridization are prognostic markers in invasive ductal breast carcinomas.
AIMS The aim of this work is the study of the prognostic significance of the chromosomal aberrations described in a series of invasive ductal breast carcinomas. METHODS AND RESULTS We analysed by comparative genomic hybridization a group of 70 formalin-fixed paraffin-embedded invasive ductal breast carcinomas. Aberrations showed a frequency similar to previous studies using frozen tumours. In...
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Intrahepatic cholangiocarcinoma (ICC), a malignant neoplasm of the biliary epithelium,is usually fatal because of difficulty in early diagnosis and lack of availability of effective therapy. The genetic mechanisms involved in the development of ICC are not well understood and only a few cytogenetic studies of ICC have been published. Recently, technique of degenerate oligonucleotide primed (DOP...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2002
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.10709